Scientists Create World’s Tightest Knot: A Breakthrough in Molecular Structures

Scientists Create Worlds Tightest Knot A Breakthrough in Molecular Structures

University of Western Ontario and Chinese Academy of Sciences accidentally tie the world’s smallest knot with only 54 atoms.

In a surprising scientific breakthrough, researchers from the University of Western Ontario in Canada and the Chinese Academy of Sciences have accidentally created the world’s tightest knot. Composed of only 54 atoms, this intricate trefoil knot has surpassed previous records and offers new possibilities for understanding molecular structures. While the pursuit of this record was not the initial goal, scientists hope that unraveling the formation of this knot will lead to the development of more complex structures. This unexpected discovery opens up a world of possibilities in the field of chemistry.


The Quest for Smaller Molecular Knots

For decades, chemists have been striving to create smaller and smaller molecular knots. These intricate structures have the potential to unlock a deeper understanding of complex molecular interactions. The recent achievement by the University of Western Ontario and the Chinese Academy of Sciences brings us closer to the quantum theoretical limit of how small a trefoil knot can be.

Accidental Discovery

The creation of the world’s tightest knot was not a deliberate pursuit. The research team was initially working on metal acetylides, a type of hydrocarbon used in organic chemical reactions. However, when gold acetylide was connected with diphosphine ligand, a surprising result occurred. The formation of a gold-carbon-phosphorus formula, known as Au6, led to the accidental creation of a 54-atom trefoil knot.

Ranking Knot Tightness

There is no absolute measure of knot tightness, but scientists use a metric called the backbone crossing ratio (BCR) to rank knots. The BCR is calculated by dividing the number of atoms in the knot by the number of crossings. The lower the BCR, the tighter the knot. The previous record holder from 2020 had a BCR of 23, while the 2017 knot had a BCR of 24. The newly created trefoil knot has a remarkable BCR of 18, making it the tightest knot ever recorded.

Unraveling the Mystery

The researchers behind this groundbreaking discovery admit that they do not fully understand how this knot formed. The complexity of the system and the unexpected nature of the result make it a fascinating puzzle to solve. The accidental creation of this tight trefoil knot is a testament to the serendipitous nature of scientific exploration.

The Significance of Small Knots

While the creation of the world’s tightest knot may seem like a niche achievement, it holds significant implications for the field of chemistry. Understanding the formation and properties of molecular knots can pave the way for the development of new materials with unique properties. These intricate structures could have applications in various fields, including medicine, electronics, and nanotechnology.

The Limits of Knot Tightness

With two world records broken within seven years, the question arises: could there be an even tighter knot out there? Theoretical calculations suggest that the minimum number of atoms required for a trefoil structure is around 50. This means that the newly created knot is already approaching the quantum theoretical limit of knot tightness.

The accidental creation of the world’s tightest knot by scientists from the University of Western Ontario and the Chinese Academy of Sciences opens up exciting possibilities in the realm of molecular structures. This breakthrough not only sets a new record but also provides valuable insights into the formation and properties of intricate knots. As researchers continue to unravel the mysteries of this remarkable achievement, we can anticipate further advancements in the development of complex molecular structures. The world’s smallest knot may be just the beginning of a new era in chemistry.